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来凯LAE002乳腺癌III期临床达到主要终点_城市资讯网

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不联合CDK4/6抑制剂治疗后出现疾病进、伴PIK3CA/AKT1/PTEN改变的HR+/HER2-局部晚期或转移性乳腺癌患者,旨在评估LAE002(afuresertib)与氟维司群联合疗法的抗肿瘤疗效及安全性。研究共纳入261名受试者,其中70.5%的受试者曾接受过CDK4/6抑制剂治疗。临床结果显示,LAE002(afuresertib)联合氟维司群组的中位无进展生存期(PFS)为7.6个月

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